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Mesothelioma and Non Asbestos Exposure The majority of mesothelioma cases occur on the lung linings and abdomen. The rare cancer can also form in the lining of the heart (pericardium) or testes. Asbestos exposure is a major risk factor for mesothelioma. Some patients with mesothelioma do not have any history of asbestos exposure. Exposure to Asbestos Asbestos is a naturally occurring mineral that was previously used in industrial and construction products across the globe. Workers working in asbestos industries were exposed to asbestos each day. Asbestos fibers can become lodged in the lungs, which can lead to progressive lung disease. This is referred to as asbestosis. As time passes the fibers that are trapped can cause mesothelioma. Asbestos can also be inhaled or consumed, and the risk of mesothelioma and other asbestos-related illnesses increases with the amount and length of exposure. Most cases of mesothelioma result from occupational exposure. Asbestos was used in a variety of trades, such as construction, insulation, electrical work, automobile maintenance and pipefitting. These trades are typically heavily populated by males and, as a result, male mesothelioma cases comprise 75-80% of all reported cases. The gradual elimination of asbestos in the United States, and other first-world countries has reduced the risk of contamination. This has led to an increase in cases, with non-occupational exposure becoming more prevalent. Non-occupational Mesothelioma is caused when asbestos is released in the workplace or found at school or at home. The secondhand exposure can also trigger it, for example when a family members touches the work clothes of a asbestos worker. Those who experience this type of exposure might experience symptoms such as breathlessness or chest pain that is often mistaken as lung or heart conditions. Certain studies have found a link between non-occupational exposure and mesothelioma, but the results are inconsistent. Many of these studies were conducted on a small sample size, and within-study heterogeneity has been high. More research is needed to establish the connection between mesothelioma and exposure to non-occupational substances. Anyone who has had non-occupational asbestos exposure should speak to their doctor regarding their asbestos-related background. They should request mesothelioma testing in the event of concerns, and ask for an appointment with a specialist. Mesothelioma specialists are able to provide patients with the best treatment and care options to improve their chances of survival. They will analyze medical records and conduct imaging tests to diagnose mesothelioma. They will also offer advice on how to file a mesothelioma suit to receive compensation from an asbestos trust fund. Secondhand Exposure Asbestos exposure is the most common mesothelioma-related cause. But, it's not the only one. There is sparks asbestos lawyer to suggest that people who have never handled asbestos or worked in industries with asbestos-related activities may still develop mesothelioma. This is referred to as secondary asbestos exposure, or non-occupational asbestos exposure. Asbestos fibers are extremely small and are able to stick to hair, clothing and skin. Workers could carry harmful fibers in their work clothing at home, and then transmit them to family members. The asbestos fibers that are scattered around can be inhaled or swallowed, which can lead to mesothelioma. This form of mesothelioma is more common in women, and it usually occurs in the lung. However, it can also be found in the abdomen and the chest wall. The most commonly reported sign is a shortness of breath (dyspnea) and it may be coupled with other signs like fluid in the lungs or swelling in the scrotum. The mesothelioma that develops in the lungs is known as mesothelioma of the pleural region. Peritoneal mesothelioma refers to the name for mesothelioma that affects the stomach wall or the chest wall. This type of mesothelioma can cause a variety of symptoms like abdominal pain, difficulty breathing and constipation. A number of studies have shown that people with no previous history of exposure to asbestos could develop mesothelioma as a result of exposure to asbestos through secondhand fibers. Most often, these people have lived with someone who was exposed to the harmful substance. They could have been in contact with the clothing of the asbestos worker or had another contact with the asbestos worker. Veterans are at a greater risk of developing mesothelioma due to asbestos that was extensively used in military bases vessels, vehicles and bases. The Navy is at a greater risk since asbestos was used in the hull and gun turrets of ships to shield them from fire. In addition, sailors frequently brought asbestos back from their work on ships that were contaminated by the material. Environmental Exposure A variety of materials have been linked to mesothelioma. However, the disease is usually linked to exposure to asbestos. Asbestos, a naturally occurring mineral is used in the manufacture of products for many years. It is a heat-resistant material and durable which makes it suitable for insulation, brakes, shingles, flooring, and many other products. When asbestos is broken it releases dust which can be inhaled or swallowed. These fibers may remain in the stomach or lungs for a long time, triggering mesothelioma-related symptoms. The most frequent mesothelioma-related symptoms are breathing difficulties, abdominal pain, and chest pain. Asbestos victims might experience these symptoms for 20 to 60 years or more following their first exposure. These symptoms could be mistaken for other ailments, so it is important to see a doctor if you have these symptoms. Notifying your doctor of asbestos exposure is important. This will help avoid the wrong diagnosis and ensure you receive the appropriate treatment. The most frequent victims of mesothelioma from asbestos exposure are those who been directly exposed to asbestos but it is possible for loved family members to be affected. This is called secondary exposure. Family members could inhale or swallow asbestos fibers on the clothing of a worker, shoes, or other tools. They could be exposed to asbestos by someone bringing home these particles on their hair or clothing. This is the reason mesothelioma sufferers and their families should always be sure to wash their clothing properly after working with asbestos. There is a large amount of research that suggests the connection between exposure to asbestos and mesothelioma. However there are no definitive conclusions yet on the role of other agents. For instance there is evidence that the zeolites erionite and chlorosotile may cause mesothelioma. Erionite is found in soil and rocks in certain regions of Turkey in which pleural mesothelioma rates are high. The study on the connection between asbestos and mesothelioma continues. Funnel plots have indicated the possibility of bias in publication, and there is a high degree of heterogeneity between studies. However, it is still evident that asbestos exposure in the workplace is the most significant risk factor for mesothelioma. Genetics Mesothelioma is an uncommon disease caused by malignant mesothelial cells which expand beyond control and invade surrounding tissues. It can also spread through the body through the blood or lymphatic system, which can affect other organs. Asbestos is the main reason, but it's not the only factor. Other genetic and environmental factors can trigger the condition. Certain cases of mesothelioma have been reported in people who didn't directly expose themselves to asbestos. These are referred to as non-occupational mesothelioma sufferers. They typically experienced indirect exposure through the handling of contaminated clothing or household items by an asbestos-exposed individual within their household. For instance, it is possible for one to be diagnosed with pleural mesothelioma due to the exposure to asbestos fibers in a loved one's clothing. Studies have shown that this kind of mesothelioma has an extended latency time and is more likely to affect women than men. Scientists are investigating the possibility that mesothelioma-related genetic predispositions could be a factor in its development. Recent studies have shown that mutations in BAP1 gene increases the risk of mesothelioma among those who have been exposed to asbestos. This finding is especially important, as it could be the basis for improved screening procedures for those at risk of developing mesothelioma. Researchers have discovered that a range of genes are associated with mesothelioma. These genes are usually mutated in mesothelioma and inhibit tumor growth. These genes include the major tumor suppressor homolog 2 (LATS2) and NF2. People who have mesothelioma-related family history are at a higher chance of contracting the disease. Some genes, such as BAP1, for instance, BAP1 that are passed down from parents. Asbestos was used heavily in the military for a number of years and veterans suffer from the highest rates of mesothelioma in comparison to other occupational groups. People who were in the Navy and on ships were at greatest risk because of the extensive exposure to asbestos in fireproofing, insulation materials and shipbuilding.